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Zmiany w nerkach w zespole antyfosfolipidowym

Data publikacji: 12 Luty 2020

Antiphospholipid syndrome (APS) is an autoimmune systemic disease characterized by recurrent venous and arterial thrombosis, obstetrical complications, and presence of antiphospholipid antibodies. Kidney involvement is not included in the APS diagnostic criteria, whereas in 10–40% of APS cases kidney vessels are affected. What is more, in catastrophic APS kidney involvement reaches 70%. APS is rarely detected at early stage of kidney involvement due to non-characteristic symptoms, that include changes in urine sediment and moderate hypertension. In this paper pathogenesis of APS nephropathy, and its clinical and pathologic manifestations are discussed. Finally, current recommendations in therapy and prophylaxis are presented.

Forum Nefrologiczne 2017;10(4):241–249

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